Memorandum

August 13, 2010

Please be advised, Amgen is updating the external appearance of all Sensipar^® tablet strengths.
The medicine itself and the packaging will remain the same.

The new tablets will be released in phases. Beginning August 2010, 30 mg Sensipar^® tablets
will have an updated appearance. Starting September 2010, 60 mg and 90 mg Sensipar^®
tablets will feature the new external appearance.

The tablet dosage strength markings (30 mg, 60 mg, 90 mg) and the Amgen designation will
change from the current black ink printing to a debossed marking compressed into each tablet.
The size of the tablets and green color coating will not change for any dosage strength. The picture below shows the updated appearance of the tablets, using the 30 mg tablet as an example.

Tablets not to scale; tablet size remains unchanged.

Amgen is communicating this change with healthcare professionals, patients, and other
pharmacy partners. If you have any questions, please contact Amgen Medical Information at
1-800-77-AMGEN (1-800-772-6436). For additional prescribing information about Sensipar^®,
please visit www.sensipar.com.

MC49203-C