Results

Q1. Which proton pump inhibitor (PPI) is prescribed more than all others?
B. Omeprazole. Decades after its introduction, more prescriptions are written for omeprazole than for all other PPIs combined.1
Q2. People with swallowing issues are more likely to require a PPI.
A. True. A recent study shows that severe heartburn and dysphagia are often observed concomitantly, and higher grades of dysphagia correlate with greater severity of heartburn.2
Q3. When did the FDA approve the first prescription omeprazole formulation to be dispensed as a liquid in the United States?
E. 2022. Despite being among the most-prescribed drugs of all time, omeprazole had not been available in an FDA-approved formulation that is dispensed as a liquid until KONVOMEP™ was approved in late 2022 and will become available in pharmacies in Q1 2023.3-5
Q4. How are KONVOMEP™ and OTC omeprazole tablets similar?
A, B, D, and E are the correct answers. Although KONVOMEP™ has the same active ingredient, once-a-day dosing, and 24-hour efficacy as OTC omeprazole tablets,3 and is similarly widely available in pharmacies nationwide, only KONVOMEP™ offers automatic copay support for most commercially insured patients. Eligibility restrictions and terms and conditions may apply.
Q5. How does KONVOMEP™ liquid differ from OTC omeprazole tablets?
A, B,C, D. All of the above. In addition to its shake-and-pour liquid formulation and strawberry flavor, KONVOMEP™ liquid omeprazole is also well suited for use with NG tubes.3 With automatic co-pay discounts for most commercially insured patients, prescription KONVOMEP™ may even have lower out-of-pocket costs. Eligibility restrictions and terms and conditions may apply.
Q6. Which of the following does a pharmacist need to prepare and dispense KONVOMEP™ liquid?
F. None of the above. Everything you need to prep and dispense KONVOMEP™ as a liquid suspension comes premeasured and preweighed in one box and it takes less than 3 minutes to reconstitute.3,6
Q7. How much omeprazole is in each mL of KONVOMEP™ as dispensed?
B. 2 mg. As dispensed, each mL of KONVOMEP™ delivers 2 mg of omeprazole, providing increased dosing precision and titration flexibility that is not possible with solid tablets.3
Q8. As an FDA-approved drug, how does KONVOMEP™ differ from a custom compounded liquid?
A, B, C, D. All of the aboove. As an FDA-approved drug, KONVOMEP™ liquid omeprazole is manufactured under current Good Manufacturing Practices (cGMP) to ensure uniformity of dose and consistency.3,7 KONVOMEP™ takes less than 3 minutes to prepare,6 with no mixing or measuring equipment to clean,3 and it has broader coverage than compounded formulations with fewer restrictions.8 Commercially insured patients receive automatic copay discounts at point of sale with no need for cards or coupons, and no additional pharmacist paperwork. Eligibility restrictions and terms and conditions may apply.
Q9. What does a commercially insured KONVOMEP™ user need to automatically receive KONVOMEP™ for a copay as low as $5?
E. None of the Above. Low copay discounts for commercially insured KONVOMEP™ patients are automatically applied at point of sale, with no need for cards, coupons, or preregistration, and no added paperwork for you or your staff. Eligibility restrictions and terms and conditions may apply.
Q10. Which requires the least amount of time on average?
C. It takes less than 3 minutes to prepare strawberry-flavored KONVOMEP™ prescription liquid omeprazole for patients who need an alternative to pills and tablets.6 (It is recommended that tea be steeped for ~4 minutes. According to recent research, the average top-100 song is 3 minutes and 30 seconds. The average adult can walk 400 meters in 4 minutes. Online recipes for soft-boiled eggs recommend cooking for 6 to 7 minutes.)9-12

REFERENCES: 1. Data on file. PPI Landscape. Azurity Pharmaceuticals, Inc. August 19, 2022. 2. Vakil NB, Traxler B, Levine D. Dysphagia in patients with erosive esophagitis: prevalence, severity, and response to proton pump inhibitor treatment. Clin Gastroenterol Hepatol. 2004;2(8):665-668. 3. Konvomep™ [package insert]. Wilmington, MA: Azurity Pharmaceuticals Inc; 2022. 4. Orange Book. Search term: omeprazole. US Food and Drug Administration. https://www.accessdata.fda.gov/scripts/cder/ob/search_product.cfm. Accessed November 1, 2022. 5. Konvomep™ FDA approval history. Drugs.com. https://www.drugs.com/history/konvomep.html. Updated September 3, 2022. Accessed November 2, 2022. 6. Data on file. KONVOMEP™ (omeprazole and sodium bicarbonate for oral suspension) Reconstitution Time Study. Azurity Pharmaceuticals, Inc. August 2022. 7. Current Good Manufacturing Practice (CGMP) Regulations. US Food and Drug Administration. https://www.fda.gov/drugs/pharmaceutical-quality-resources/current-good-manufacturing-practice-cgmp-regulations. Accessed November 2, 2022. 8. US Government Accountability Office. Report GAO-15-85. October 2014. https://www.gao.gov/products/gao-15-85. Accessed November 2, 2022. 9. Danahy A. How to steep tea like an expert. Healthline. https://www.healthline.com/nutrition/how-to-steep-tea. Published January 9, 2020. Accessed November 2, 2022. 10. Clark B. What’s the average length of a song? (2022). MuscianWave.com. https://www.musicianwave.com/whats-the-average-length-of-a-song-year/#top_ankor. Updated September 20, 2022. Accessed November 2, 2022. 11. How long does it take to walk 400 meters? Reference.com. https://www.reference.com/science-technology/long-walk-400-meters-b9c7cb465131925. Updated March 27, 2020. Accessed November 2, 2022. 12. How to make perfect soft or hard boiled eggs. Eggland’s Best. https://www.egglandsbest.com/news/how-to-make-perfect-soft-or-hard-boiled-eggs?gclid=Cj0KCQjwqoibBhDUARIsAH2OpWjUNQ8uP4TDYxcGKMniPDFaIT28%E2%80%A6. Published February 1, 2022. Accessed November 2, 2022.
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