Assessing Safety of Biological Home-Infusions Agents for IBD The use of biological agents to manage inflammatory bowel disease (IBD; i.e., Crohn's disease and ulcerative colitis) has grown markedly in recent years. As the concept of patient-centered medical and home-care services has expanded, patients are no longer receiving these infusions just at conventional infusion centers; they are also receiving them at home. Read more.
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Cetirizine Equally Effective, Safer Alternative to Diphenhydramine?
IV diphenhydramine has been considered the standard of care for hypersensitivity infusion reactions. However, IV diphenhydramine has an adverse-event (AE) profile that includes potent anticholinergic effects, and it is a Beer's list drug, making its use undesirable in older adults. IV cetirizine, approved in 2019 for the treatment of acute urticaria in adults, may offer a more favorable AE profile. Read more.
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