Correlating Interleukin-8 Levels and Cognitive Function in MDD
Previous research has established that selective serotonin reuptake inhibitors (SSRIs) can modify the effect of neuroinflammatory cytokines on cognitive deficits in patients with major depressive disorder (MDD); however, no studies have investigated serum interleukin-8 levels with regard to cognitive function in MDD patients with SSRIs. Learn more about a recent study that sought to investigate the correlation.

Influence of Patient Age in MDD Treatment Response
In a recent publication in the Journal of Psychiatric Research, researchers utilized participant-level data from large, NIH-sponsored trials in individuals with major depressive disorder (MDD) aged 12 to 74 years to gain a better understanding of the impact of age on response to antidepressant treatment. Learn more about the results of this study.

Assessing Gray Matter Changes in Adolescents With MDD, Bipolar Disorder
Previous research indicated that gray matter volume alterations are associated with mood disorders, but findings have not been consistent in various studies involving adolescents with major depressive disorder (MDD) or bipolar disorder. Learn more about results from a study published in the Journal of Affective Disorders that found adolescents with MDD demonstrated altered gray matter volume.