June 28, 2024

Retail Pharmacy Dispensing of Naloxone Increases

Retail pharmacists are dispensing an increasing number of naloxone prescriptions, but opioid overdoses continue to soar in the United States—contributing to over 107,000 deaths. Public health officials suggest that coprescribing with high-risk opioids might be one answer, with reducing financial barriers another way to increase the use of the lifesaving drug. Read more.

Advertisement

PPI Use in Critically Ill Adults on Breathing Machines

Recent studies have raised questions about the use of proton pump inhibitors (PPIs) to help prevent upper gastrointestinal bleeding in critically ill adults on breathing machines. Find out how a new global study and meta-analysis answers these concerns and why the authors recommend the use of gastric acid suppressants in those patients.

Supplements Improve Walking Endurance in PAD Patients

Not many treatments are available for peripheral artery disease (PAD), which causes increased oxidative stress, impaired mitochondrial activity, and poor walking performance. A new study raises the possibility, however, that a common OTC supplement, nicotinamide riboside, significantly improves walking endurance in those patients. Read more.

Advertisement

Sacubitril/Valsartan Not Linked to Higher Dementia Rates

Recent hypothetical concerns were raised about the use of angiotensin receptor/neprilysin inhibitors, such as sacubitril/valsartan, in heart failure patients. The worry was that neprilysin might degrade amyloid-beta peptides in the brain and increase the risk of Alzheimer’s dementia. Find out how a substudy of the PARAGON-HF trial successfully resolves those concerns.

 
Facebook   Twitter   USP Google App   USP itunes App
U.S. Pharmacist
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Advertisement Advertisement