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Some High-Dose ADHD Stimulants Linked to Psychosis, Mania
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Significant dose-related episodes of psychosis and mania were seen with large doses of amphetamine for attention-deficit/hyperactivity disorder (ADHD) in adults, but this was not the case with methylphenidate, marketed as Ritalin, according to a new study. The researchers cautioned about the adverse effects of higher dosages and suggested that prescribers opt for medications other than amphetamines in patients at high risk for psychosis or mania. Read more.
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Guidelines Suggest Naloxone Dispensing With Pediatric Opioids
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For the first time, the American Academy of Pediatrics has issued clinical guidelines on prescribing opioids in children and adolescents. The specialty group calls for routine dispensing of naloxone to treat overdoses with any pediatric opioid prescription. Find out why that is the case and what else the guidelines address.
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Study: GLP-1 RAs Show Promise for Reducing Cirrhosis
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According to a recent study, glucagon-like peptide 1 receptor agonists (GLP-1 RAs) might be able to reduce the incidence of cirrhosis, hepatocellular carcinoma, and mortality in patients with metabolic dysfunction–associated steatotic liver disease and diabetes. But there is a catch: Treatment has to be introduced early in the course of the disease to obtain those positive effects. Read more.
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Self-Administered Flu Vaccine Approved for Younger Americans
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The approval of the first self-administered influenza vaccine probably will not reduce pharmacies’ fall workload very much. For one thing, the majority of those receiving vaccines are aged older than 50 years, and the product approved for self-administration, FluMist, is approved for those aged 2 to 49 years and can be administered by a pharmacist or other healthcare provider. Read more.
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